Low serum concentration of free triiodothyronine (FT3) is associated with increased risk of Alzheimer's disease
Objective: To examine the relation between THs and the risk of Alzheimer’s Disease (AD) or vascular dementia (VaD) in a memory clinic population.
Results:
Inverse, linear association between serum FT3 and risk of ADK
Higher serum FT3 was associated with lower risk of conversion to AD
Patients in the lowest serum FT3 quartile had a twofold increased risk of AD compared to those in the highest quartile
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Quinlan P, Horvath A, Wallin A, Svensson J. Low serum concentration of free triiodothyronine (FT3) is associated with increased risk of Alzheimer's disease. Psychoneuroendocrinology. 2019;99:112-119. doi:10.1016/j.psyneuen.2018.09.002