The Role of Estrogen in Men
How Do Men Make Estradiol?
Aromatase is the enzyme that converts testosterone to estrogen. Estrogen receptors are abundant in the brain, penis and testis.
Brain
Estrogen receptors in the pre-optic area and anterior hypothalamus have high levels of aromatase and estrogen receptors which regulate libido.
Penis
The penile vasculature and urothelium are lined with estrogen receptors. In the mature penis, estradiol modulates testosterone with the overall effect being detrimental to erectile function.
Testis
Leydig, Sertoli and Germ cells all produce estrogen at various stages of testes development leading to testosterone modulation. An inappropriate increase in estradiol leads to a decrease in testicular size and sperm production.
EMBRACE YOUR BEST SELF
From hormone optimization to cartilage regeneration, we create personalized treatment plans based on thorough testing and monitoring.
We treat our patients for their unique needs and symptoms, rather than simply viewing lab results. We go beyond the numbers to alleviate our patient’s symptoms and get them back to living the lives they want to live.
